hedgegrail pharmacy logo
We use cookies to enhance your browsing experience. By clicking 'I Understand and Accept', you consent to our use of cookies.
I understand and accept
No, I don't want to use cookies
My Account
Control Panel
An example toast message
Do Something
Login
en
en
hedgegrail pharmacy logo
Menu
en
en
Change Language
Login
My Account
Control Panel
Pharmacy First
Pharmacy Services
Our Store
Health Advice
Order
Log Out
Login
Login
en
en
Do Something
Login
en
en
hedgegrail pharmacy logo
Menu
en
en
Change Language
Login
My Account
Control Panel
Pharmacy First
Pharmacy Services
Our Store
Health Advice
Order
Log Out
Login
Login
en
en
Causes

The exact cause of polycystic ovary syndrome (PCOS) is unknown, but it's thought to be related to abnormal hormone levels.

Resistance to insulin

Insulin is a hormone produced by the pancreas to control the amount of sugar in the blood. It helps to move glucose from blood into cells, where it's broken down to produce energy.

Insulin resistance means the body's tissues are resistant to the effects of insulin. The body therefore has to produce extra insulin to compensate.

High levels of insulin causes the ovaries to produce too much testosterone, which interferes with the development of the follicles (the sacs in the ovaries where eggs develop) and prevents normal ovulation.

Insulin resistance can also lead to weight gain, which can make PCOS symptoms worse, as having excess fat causes the body to produce even more insulin.

Hormone imbalance

Many women with PCOS are found to have an imbalance in certain hormones, including:

  • raised levels of testosterone – a hormone often thought of as a male hormone, although all women usually produce small amounts of it
  • raised levels of luteinising hormone (LH) – this stimulates ovulation, but may have an abnormal effect on the ovaries if levels are too high
  • low levels of sex hormone-binding globulin (SHBG) – a protein in the blood that binds to testosterone and reduces its effect
  • raised levels of prolactin (only in some women with PCOS) – a hormone that stimulates the breast glands to produce milk in pregnancy

The exact reason why these hormonal changes occur is not known.

It's been suggested that the problem may start in the ovary itself, in other glands that produce these hormones, or in the part of the brain that controls their production. 

The changes may also be caused by the resistance to insulin.

Genetics

PCOS sometimes runs in families. If any relatives, such as your mother, sister or aunt, have PCOS, the risk of you developing it is often increased.

This suggests there may be a genetic link to PCOS, although specific genes associated with the condition have not yet been identified.

Last Reviewed
13 October 2022
NHS websiteNHS website
hedgegrail pharmacy logo
Hedgegrail Pharmacy in Stoke Poges offers a wide range of prescription and over-the-counter medications, as well as health and beauty products
Company Registration: 2041755
Premises GPhC: 1099892
Superintendent: Baljit Singh Bahra
Do Something
Do Something
Menu
Pharmacy First
All Pharmacy First Services
Earache
Impetigo
Insect Bite
Shingles
Sinusitis
Sore Throat
Urinary Tract Infections (UTIs)
Pharmacy Services
Order Prescriptions
Our Store
Health Advice
Opening Hours
Store Hours Unavailable
No store selected for opening hours
Loading Open Hours...
Hedgegrail Pharmacy © 2024
Privacy Policy